Applications
| Reactive Species | Human, Mouse, Rat |
| Specificity | The antibody detects endogenous Histone H1 (Mono Methylatedl Lys25) protein. |
| Validated Applications | WB |
| Recommended Dilution | WB 1:500-1000 |
Product Information
| Product Name | Histone H1 (Mono Methylatedl Lys25) Mouse pAb |
| Antibody Type | Mouse pAb |
| Immunogen | Synthetic Peptide of Histone H1 (Mono Methylatedl Lys25) |
| Modification | Methylated |
| Host | Mouse |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | N/A |
| Conjugation | Unconjugated |
| Form | Liquid |
| Concentration | N/A |
| Purification Method | Immunogen affinity purification |
| Storage Buffer | PBS (pH 7.4) containing 0.5% BSA, 0.02% New type preservative N as Preservative and 50% Glycerol. |
| Storage Conditions | Store at 2-8°C for up to 2 weeks. Store at -15°C to -25°C for 1 year. Aliquot to avoid freeze / thaw cycle. |
Background Information
| Function | function:Histones H1 are necessary for the condensation of nucleosome chains into higher order structures.,similarity:Belongs to the histone H1/H5 family., |
| UniProt ID | Q02539/P16403/P16402/P10412 |
| Organism | Human |
| Recommended Name | Histone H1.1/Histone H1.2/Histone H1.3/Histone H1.4 |
| Short Name | N/A |
| Alternative Names | H1K25ME1, HIST1H1A, H1F1, Histone H1.1, Histone H1a, HIST1H1C, H1F2, Histone H1.2, Histone H1c, Histone H1d, Histone H1s-1, HIST1H1D, H1F3, Histone H1.3, Histone H1c, Histone H1s-2, HIST1H1E, H1F4, Histone H1.4, Histone H1b, Histone H1s-4. |
| Gene ID | 3024/3006/3007/3008 |
| Gene Name | HIST1H1A/HIST1H1C/HIST1H1D/HIST1H1E |
| Calculated MW | 17-25 kDa |
| Observed MW | N/A |
| Subcellular Location | Nucleus . Chromosome . Mainly localizes in euchromatin. |
| Summary | Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015], |
| Pathways | N/A |
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Histone H1 (Mono Methylatedl Lys25) Mouse pAb
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